Compare online weight loss plans and personalized support across five leading programs, with real pricing, medication options, shipping speed, and provider requirements sourced directly from each provider so you can choose with confidence.
See the rankings ↓Fast-turnaround telehealth intake with next-day shipping from US-licensed pharmacies.
TrimRx pairs an online medical evaluation with prescription fulfillment through state-licensed US pharmacies. It's built for people who want to move quickly from sign-up to their first shipment, with a straightforward, no-membership pricing structure.
Membership pricing that's locked in for life, with no mid-year price hikes.
AltRx runs a membership model built around price stability: whatever tier you join at is the price you keep paying, even as list prices rise. Telehealth consultations are handled by an affiliated medical practice, and plans are FSA/HSA eligible.
Flat, all-inclusive monthly pricing with unlimited telehealth visits built in.
Sunlight bundles medication, provider visits, required lab work, and shipping into one flat monthly rate rather than charging separate access or visit fees. It's a newer entrant in the space, and pricing is competitive, though it's worth reading recent independent reviews on support responsiveness before committing to a longer plan.
Highest-rated of the group, with an introductory first-month discount.
Sprout Health connects patients with licensed US providers and compounding pharmacies for ongoing GLP-1 treatment, with monthly check-ins and refill management handled through an online portal. New patients get a reduced first-month rate before the plan moves to its standard monthly price.
Both injectable and oral options, with doctor visits bundled into the price.
Direct Meds offers compounded semaglutide and tirzepatide as injections or oral sublingual drops, with telemedicine visits included at no extra charge. Pricing is tiered by medication and format, with a discounted first month for new patients.
| Provider | Score | Starting price | Medications offered | Insurance required | Avg. shipping | FSA/HSA eligible |
|---|---|---|---|---|---|---|
| TrimRx | 9.6/10 | $149/mo | Compounded semaglutide & tirzepatide | No | 1-2 days | N/A |
| AltRx | 9.1/10 | $89/mo | Compounded semaglutide & tirzepatide | No | Free | Yes |
| Sunlight | 8.4/10 | $159/mo | Compounded semaglutide & tirzepatide | No | 1-2 days | Yes |
| Sprout Health | 9.3/10 | $149 first mo. / $299/mo after | Compounded GLP-1 & GIP/GLP-1 | No | Discreet, to door | N/A |
| Direct Meds | 9.0/10 | $147 first mo. (from $297/mo) | Semaglutide & tirzepatide, injectable or oral | No | 1-2 days | Yes |
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Fill out a health questionnaire covering your medical history, current weight, and goals.
A licensed clinician reviews your intake and decides whether treatment is appropriate for you.
If approved, a licensed pharmacy prepares and ships your prescription, typically within 1-3 days.
This is a general overview, not a complete list of contraindications or side effects. Your provider will review your full medical history before prescribing.
GLP-1 receptor agonists are a class of medications originally developed to treat type 2 diabetes. Certain brand-name versions are also FDA-approved for chronic weight management in adults who meet specific medical criteria. Whether one is appropriate for you is a decision made by a licensed provider based on your health history.
Often, no. Many telehealth weight-loss providers dispense compounded versions of these medications through licensed compounding pharmacies. Compounded medications are not FDA-approved, meaning the FDA has not independently reviewed them for safety, effectiveness, or quality, even though the pharmacies preparing them operate under state licensing and federal compounding regulations. Always check a specific provider's own disclosures for details.
Generally no. Most direct-to-consumer GLP-1 telehealth programs are self-pay and don't require insurance, though some accept FSA/HSA funds. Coverage rules vary by employer and insurer, so it's worth checking your own plan if you'd prefer to bill insurance instead.
Each provider's 1-10 score and rank position reflect a mix of publicly listed pricing, stated shipping timelines, plan flexibility, and reported customer ratings at the time of writing. This is editorial content, not a personalized medical recommendation, and pricing or promotions can change after publication, so always confirm current details on the provider's own site.
No. This page is for general informational purposes only. It doesn't replace a consultation with a licensed healthcare provider, who can evaluate your medical history and determine whether a GLP-1 medication is appropriate for you.